Enzyme - EC
1.14.16.1 - Phenylalanine 4-monooxygenase
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EC
1.14.16.1
Official
Name
Phenylalanine 4-monooxygenase
Alternative
name(s)
Phenylalanine 4-hydroxylase
Phenylalaninese
PAH
Phenylalaninese
PAH
Class
1.Oxidoreductases
14.Acting on paired donors with incorporation of molecular oxygen
16.With reduced pteridine as one donor, and incorporation of one atom of oxygen
14.Acting on paired donors with incorporation of molecular oxygen
16.With reduced pteridine as one donor, and incorporation of one atom of oxygen
Reaction
catalysed
L-Phenylalanine
+ Tetrahydrobiopterin + O2
L-Tyrosine
+ Dihydrobiopterin + H2O
L-Tyrosine
+ Dihydrobiopterin + H2OSubstrates
L-Phenylalanine
Tetrahydrobiopterin
O2
Tetrahydrobiopterin
O2
Products
L-Tyrosine
Dihydrobiopterin
H2O
Dihydrobiopterin
H2O
Cofactor
Iron
Metabolic
Pathways
Other
comments
The mammalian enzyme is an iron protein.
Belongs to the Biopterin-dependent aromatic amino acid hydroxylases group.