Enzyme - EC 2.4.1.11 - Glycogen (starch) synthase
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The tridimensional structure of this enzyme has not been resolved yet.
EC
2.4.1.11
Official Name
Glycogen (starch) synthase
Alternative Name(s)
UDP-glucose-glycogen glucosyltransferase
Class
2.Transferases
4.Glycosyltransferases
1.Hexosyltransferases
4.Glycosyltransferases
1.Hexosyltransferases
Catalysed reaction
UDP-glucose + {(1,4)-a-D-glucosyl}(N)
UDP
+ {(1,4)-a-D-glucosyl}(N+1)
UDP
+ {(1,4)-a-D-glucosyl}(N+1)Substrates
UDP-glucose
(1,4-a-D-glucosyl)n
Glucosylated glycogenin
(1,4-a-D-glucosyl)n
Glucosylated glycogenin
Products
UDP
(1,4-a-D-glucosyl)n+1
(1,4-a-D-glucosyl)n+1
Metabolic Pathways
Other comments
The recommended name varies according to the source of the enzyme and the nature of its synthetic product.
Glycogen synthase from animal tissues is a complex of a catalytic subunit and the protein glycogenin. The enzyme requires glucosylated glycogenin as a primer; this is the reaction product of EC 2.4.1.186. A similar enzyme utilizes ADP-glucose (EC 2.4.1.21).